Sofradex ear drops: price, use & side effects

Sofradex ear drops are a prescription-only medication in Australia, specifically formulated to treat otitis externa (commonly known as swimmer’s ear). This condition involves inflammation and infection of the external ear canal. Sofradex combines anti-inflammatory, antibacterial, and antifungal agents to address various symptoms and causes of ear infections.
How does Sofradex ear drops work?
Sofradex ear drops contain a combination of antibiotics and a corticosteroid. The antibiotics—framycetin sulfate and gramicidin—help kill bacteria that cause infections, while dexamethasone, a steroid, reduces inflammation, redness, and swelling. This triple-action formula is effective in treating external ear infections that are both bacterial and inflammatory in nature.
How to use Sofradex ear drops
To use Sofradex ear drops correctly:
- Wash your hands thoroughly.
- Warm the bottle slightly by holding it in your hands (to prevent dizziness caused by cold liquid in the ear).
- Tilt your head or lie down with the affected ear facing up.
- Drop the prescribed number of drops into the ear canal.
- Keep your head tilted for a few minutes or insert a small piece of cotton if instructed by your doctor.
- Repeat for the other ear if needed.
- Do not insert the dropper into the ear to avoid contamination or injury.
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Sofradex ear drops dosage
The standard recommended dosage is 2 to 3 drops in the affected ear(s) three to four times daily, depending on the severity of the infection. However, the exact dosage should always be determined by your doctor based on your condition and response to treatment.

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Sofradex ear drops: composition & ingredients
Each ml of Sofradex contains:
- Framycetin sulfate (5 mg) – an aminoglycoside antibiotic
- Gramicidin (0.05 mg) – a polypeptide antibiotic
- Dexamethasone sodium metasulfobenzoate (0.5 mg) – a corticosteroid
- Other excipients include sodium citrate, citric acid, and chlorocresol as a preservative
What are Sofradex ear drops used for?
Sofradex ear drops are primarily used to treat:
- Bacterial outer ear infections (otitis externa)
- Inflammation of the external auditory canal
- Itchy, painful, or red ears caused by bacterial infection
In some cases, they may also be prescribed for infected eczema around the ear canal or for certain eye infections, although this use is less common and should only be under medical supervision.
If you are experiencing symptoms of an ear infection or inflammation, you can book a free hearing test here.
How often can I use Sofradex ear drops?
How long should I use Sofradex ear drops?

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Where to buy Sofradex ear drops?

Sofradex ear drops are prescription-only medication in many countries and can be purchased at:
- Local pharmacies (with a prescription)
- Online pharmacies (Chemist Warehouse)
- Medical supply websites
Always make sure to buy from reputable sources and consult your doctor before use

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Sofradex ear drops: side effects
Common side effects include:
- Temporary stinging or burning in the ear
- Irritation or itching
- Allergic reactions (rash, swelling, redness)
Less common but serious side effects (especially with prolonged use):
- Thinning of the skin in the ear canal
- Secondary fungal infections
- Increased intraocular pressure (if used near or in the eyes)
Stop using the drops and consult a doctor if you experience persistent pain, swelling, or signs of an allergic reaction.
Sofradex ear drops age
Sofradex is generally not recommended for children under 2 years old unless specifically advised by a doctor. In older children and adults, it can be used safely when prescribed appropriately. Always follow your doctor's advice regarding age-related use.
Sofradex ear drops during pregnancy
If you’re pregnant and considering using Sofradex ear drops, it’s important to exercise caution and consult your healthcare provider first. Sofradex contains a combination of antibiotics and corticosteroids, which may pose risks during pregnancy if not used appropriately.
Here’s what you should know:
- Safety Category: Sofradex is generally classified as a category C medicine during pregnancy, meaning that there is limited data on its safety, and it should only be used if the potential benefits justify the potential risks to the fetus.
- Potential Risks: The corticosteroid component (dexamethasone) may affect fetal development if absorbed in significant amounts, though topical application in the ear typically results in minimal systemic absorption.
- When to Use: Your doctor may prescribe Sofradex during pregnancy if the ear infection or inflammation is severe and other safer alternatives are unavailable or ineffective.
- Avoid Self-Medication: Never use Sofradex ear drops during pregnancy without medical advice. If you experience ear symptoms, speak with your healthcare provider to determine the safest treatment options for you and your baby.
Sofradex ear drops price
The price of Sofradex ear drops varies by country and pharmacy. On average, an 8ml bottle may cost between $10 and $18 AUD.
Prices may also differ depending on whether the drops are generic or branded, and whether they are covered by insurance or prescription plans.
Sofradex ear drops: reviews and complaints
Sofradex ear drops are a widely prescribed treatment for ear infections and inflammation. They are especially known for treating conditions like otitis externa (also known as swimmer’s ear). Reviews are generally positive, with many users reporting quick relief from pain, itching, and inflammation.
However, some users have raised concerns about side effects such as stinging upon application or allergic reactions. A few complaints also revolve around the limited shelf life after opening and the need for refrigeration in some climates.
Sofradex ear drops alternative
If Sofradex ear drops aren’t suitable or available, there are several alternatives that may be recommended depending on your condition. Common alternatives include:
- Ciprofloxacin ear drops: an antibiotic for bacterial ear infections
- Hydrocortisone ear drops: used to reduce inflammation
- Otomize ear drops: combines steroid and antibiotic effects, similar to Sofradex
- Cortisporin ear drops: another combination of antibiotic and steroid for ear infections
Always consult your healthcare provider before switching or trying alternatives to ensure the best treatment for your condition.
FAQs about Sofradex ear drops
Can you buy sofradex ear drops over the counter?
In Australia, Sofradex ear drops are not available over the counter—you must have a valid prescription from a doctor or nurse practitioner.
Here’s what you need to know:
- Sofradex is classified as a Schedule 4 (Prescription Only Medicine) and can only be dispensed with a prescription.
- Leading pharmacies such as Chemist Warehouse, Good Price Pharmacy, and SuperPharmacy require you to present a prescription (either electronic or paper) before filling the order.
- You may access it through the PBS (Pharmaceutical Benefits Scheme) with subsidised pricing, but again, only with a prescription.
Are Otodex and Sofradex the same?
No, Otodex and Sofradex are not exactly the same, but they are quite similar. Both are ear drops that combine antibiotics and steroids to treat ear infections and inflammation.
- Sofradex contains dexamethasone (a steroid), framycetin (an antibiotic), and gramicidin (another antibiotic).
- Otodex also contains dexamethasone and antibiotics, but the exact antibiotic combination can differ slightly depending on the manufacturer.
They have similar uses but may vary in ingredients or formulation.
Always check with your doctor or pharmacist before switching between them to make sure you’re using the right treatment.
Does Sofradex clear ear wax?
They are used to treat ear infections and inflammation but won’t remove or soften ear wax.
For ear wax removal, specific ear drops or professional cleaning are recommended.
Is Sofradex an antibiotic?
It includes antibiotics (like framycetin) to fight bacterial infections, along with a steroid to reduce inflammation.
So, it’s an antibiotic ear drop used mainly for treating infected or inflamed ears.
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